Human Immunodeficiency Virus
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چکیده
The human immunodeficiency viruses (HIV -1 and HIV -2), the etiological agents of the acquired immune deficiency syndrome (AIDS), beIong to the lentivirus subfamily of the Retroviridae famiIy. Sequence ana1ysis of viral DNA indicates a separate ancestral lineage for HIV 1 and HIV -2. PhyIogenetic anaIysis of diverse geographical isolates has shown HIV-l to cluster into two distinct major groups and HIV-2 into another. Multiple viral clades (subtypes) exist on the basis of sequence diversity within these groups, but these are not the same as virus serotypes which are based on antigenic diversity.
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